BDBM21190 4-(2-{[5-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-yl]amino}ethyl)phenol::CHEMBL113142::ZM 241385::ZM241385::[3H]-ZM241385

SMILES: Nc1nc(NCCc2ccc(O)cc2)nc2nc(nn12)-c1ccco1

InChI Key: InChIKey=PWTBZOIUWZOPFT-UHFFFAOYSA-N

Data: 112 KI  16 IC50  4 Kd  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 134 hits for monomerid = 21190   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenosine receptor A2a (Human)	BDBM21190 (CHEMBL113142 | 4-(2-{[5-amino-2-(furan-2-yl)-[1,2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.220	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Human)	BDBM21190 (CHEMBL113142 | 4-(2-{[5-amino-2-(furan-2-yl)-[1,2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.220	n/a	n/a	n/a	7.4	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Rat)	BDBM21190 (CHEMBL113142 | 4-(2-{[5-amino-2-(furan-2-yl)-[1,2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.330	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Adenosine receptor A2b (Human)	BDBM21190 (CHEMBL113142 | 4-(2-{[5-amino-2-(furan-2-yl)-[1,2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Human)	BDBM21190 (CHEMBL113142 | 4-(2-{[5-amino-2-(furan-2-yl)-[1,2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.830	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Human)	BDBM21190 (CHEMBL113142 | 4-(2-{[5-amino-2-(furan-2-yl)-[1,2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Adenosine receptor A2b (Human)	BDBM21190 (CHEMBL113142 | 4-(2-{[5-amino-2-(furan-2-yl)-[1,2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	95	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Human)	BDBM21190 (CHEMBL113142 | 4-(2-{[5-amino-2-(furan-2-yl)-[1,2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	81	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Human)	BDBM21190 (CHEMBL113142 | 4-(2-{[5-amino-2-(furan-2-yl)-[1,2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Human)	BDBM21190 (CHEMBL113142 | 4-(2-{[5-amino-2-(furan-2-yl)-[1,2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Human)	BDBM21190 (CHEMBL113142 | 4-(2-{[5-amino-2-(furan-2-yl)-[1,2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Human)	BDBM21190 (CHEMBL113142 | 4-(2-{[5-amino-2-(furan-2-yl)-[1,2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Human)	BDBM21190 (CHEMBL113142 | 4-(2-{[5-amino-2-(furan-2-yl)-[1,2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Human)	BDBM21190 (CHEMBL113142 | 4-(2-{[5-amino-2-(furan-2-yl)-[1,2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	286	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Human)	BDBM21190 (CHEMBL113142 | 4-(2-{[5-amino-2-(furan-2-yl)-[1,2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Human)	BDBM21190 (CHEMBL113142 | 4-(2-{[5-amino-2-(furan-2-yl)-[1,2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Human)	BDBM21190 (CHEMBL113142 | 4-(2-{[5-amino-2-(furan-2-yl)-[1,2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	<1.00E+5	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Human)	BDBM21190 (CHEMBL113142 | 4-(2-{[5-amino-2-(furan-2-yl)-[1,2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Human)	BDBM21190 (CHEMBL113142 | 4-(2-{[5-amino-2-(furan-2-yl)-[1,2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Human)	BDBM21190 (CHEMBL113142 | 4-(2-{[5-amino-2-(furan-2-yl)-[1,2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Human)	BDBM21190 (CHEMBL113142 | 4-(2-{[5-amino-2-(furan-2-yl)-[1,2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.678	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Adenosine receptor A2b (Human)	BDBM21190 (CHEMBL113142 | 4-(2-{[5-amino-2-(furan-2-yl)-[1,2,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Human)	BDBM21190 (CHEMBL113142 | 4-(2-{[5-amino-2-(furan-2-yl)-[1,2,...) Show SMILES Show InChI	GoogleScholar	UniChem		0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Rat)	BDBM21190 (CHEMBL113142 | 4-(2-{[5-amino-2-(furan-2-yl)-[1,2,...) Show SMILES Show InChI	GoogleScholar	UniChem		0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Human)	BDBM21190 (CHEMBL113142 | 4-(2-{[5-amino-2-(furan-2-yl)-[1,2,...) Show SMILES Show InChI	GoogleScholar	UniChem		0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Human)	BDBM21190 (CHEMBL113142 | 4-(2-{[5-amino-2-(furan-2-yl)-[1,2,...) Show SMILES Show InChI	GoogleScholar	UniChem		0.302	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Human)	BDBM21190 (CHEMBL113142 | 4-(2-{[5-amino-2-(furan-2-yl)-[1,2,...) Show SMILES Show InChI	GoogleScholar	UniChem		0.302	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Human)	BDBM21190 (CHEMBL113142 | 4-(2-{[5-amino-2-(furan-2-yl)-[1,2,...) Show SMILES Show InChI	GoogleScholar	UniChem		0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Human)	BDBM21190 (CHEMBL113142 | 4-(2-{[5-amino-2-(furan-2-yl)-[1,2,...) Show SMILES Show InChI	GoogleScholar	UniChem		0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Human)	BDBM21190 (CHEMBL113142 | 4-(2-{[5-amino-2-(furan-2-yl)-[1,2,...) Show SMILES Show InChI	GoogleScholar	UniChem		0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Human)	BDBM21190 (CHEMBL113142 | 4-(2-{[5-amino-2-(furan-2-yl)-[1,2,...) Show SMILES Show InChI	GoogleScholar	UniChem		0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Human)	BDBM21190 (CHEMBL113142 | 4-(2-{[5-amino-2-(furan-2-yl)-[1,2,...) Show SMILES Show InChI	GoogleScholar	UniChem		0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Human)	BDBM21190 (CHEMBL113142 | 4-(2-{[5-amino-2-(furan-2-yl)-[1,2,...) Show SMILES Show InChI	GoogleScholar	UniChem		0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Human)	BDBM21190 (CHEMBL113142 | 4-(2-{[5-amino-2-(furan-2-yl)-[1,2,...) Show SMILES Show InChI	GoogleScholar	UniChem		0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Human)	BDBM21190 (CHEMBL113142 | 4-(2-{[5-amino-2-(furan-2-yl)-[1,2,...) Show SMILES Show InChI	GoogleScholar	UniChem		0.870	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Rat)	BDBM21190 (CHEMBL113142 | 4-(2-{[5-amino-2-(furan-2-yl)-[1,2,...) Show SMILES Show InChI	GoogleScholar	UniChem		0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Rat)	BDBM21190 (CHEMBL113142 | 4-(2-{[5-amino-2-(furan-2-yl)-[1,2,...) Show SMILES Show InChI	GoogleScholar	UniChem		0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Human)	BDBM21190 (CHEMBL113142 | 4-(2-{[5-amino-2-(furan-2-yl)-[1,2,...) Show SMILES Show InChI	GoogleScholar	UniChem		0.910	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Human)	BDBM21190 (CHEMBL113142 | 4-(2-{[5-amino-2-(furan-2-yl)-[1,2,...) Show SMILES Show InChI	GoogleScholar	UniChem		0.930	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Human)	BDBM21190 (CHEMBL113142 | 4-(2-{[5-amino-2-(furan-2-yl)-[1,2,...) Show SMILES Show InChI	GoogleScholar	UniChem		1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Rat)	BDBM21190 (CHEMBL113142 | 4-(2-{[5-amino-2-(furan-2-yl)-[1,2,...) Show SMILES Show InChI	GoogleScholar	UniChem		1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Human)	BDBM21190 (CHEMBL113142 | 4-(2-{[5-amino-2-(furan-2-yl)-[1,2,...) Show SMILES Show InChI	GoogleScholar	UniChem		1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Rat)	BDBM21190 (CHEMBL113142 | 4-(2-{[5-amino-2-(furan-2-yl)-[1,2,...) Show SMILES Show InChI	GoogleScholar	UniChem		1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Human)	BDBM21190 (CHEMBL113142 | 4-(2-{[5-amino-2-(furan-2-yl)-[1,2,...) Show SMILES Show InChI	GoogleScholar	UniChem		1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Human)	BDBM21190 (CHEMBL113142 | 4-(2-{[5-amino-2-(furan-2-yl)-[1,2,...) Show SMILES Show InChI	GoogleScholar	UniChem		1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Rat)	BDBM21190 (CHEMBL113142 | 4-(2-{[5-amino-2-(furan-2-yl)-[1,2,...) Show SMILES Show InChI	GoogleScholar	UniChem		1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Human)	BDBM21190 (CHEMBL113142 | 4-(2-{[5-amino-2-(furan-2-yl)-[1,2,...) Show SMILES Show InChI	GoogleScholar	UniChem		1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Human)	BDBM21190 (CHEMBL113142 | 4-(2-{[5-amino-2-(furan-2-yl)-[1,2,...) Show SMILES Show InChI	GoogleScholar	UniChem		1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Human)	BDBM21190 (CHEMBL113142 | 4-(2-{[5-amino-2-(furan-2-yl)-[1,2,...) Show SMILES Show InChI	GoogleScholar	UniChem		1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Human)	BDBM21190 (CHEMBL113142 | 4-(2-{[5-amino-2-(furan-2-yl)-[1,2,...) Show SMILES Show InChI	GoogleScholar	UniChem		1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair