BDBM2139 1-(5-chloropyridin-2-yl)-3-[2-(2-fluoro-3,6-dimethoxyphenyl)ethyl]thiourea::LY300046HCl Analog 25::N-[2-(3,6-Dimethoxy-2-fluorophenethyl)]-N-[2-(5-chloropyridyl)]thiourea::PETT deriv.

SMILES COc1ccc(OC)c(CCNC(=S)Nc2ccc(Cl)cn2)c1F

InChI Key InChIKey=ALLWDYBEXBKRLB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 2139   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM2139(1-(5-chloropyridin-2-yl)-3-[2-(2-fluoro-3,6-dimeth...)
Affinity DataIC50:  1nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM2139(1-(5-chloropyridin-2-yl)-3-[2-(2-fluoro-3,6-dimeth...)
Affinity DataIC50:  54nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1127,L687I]/[588-1147,L687I](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM2139(1-(5-chloropyridin-2-yl)-3-[2-(2-fluoro-3,6-dimeth...)
Affinity DataIC50:  80nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed