BDBM2155 3-[2-(1H-1,3-benzodiazol-2-yl)ethyl]-1-(5-bromopyridin-2-yl)thiourea::LY300046HCl Analog 41::N-[2-(2-Benzimidazolyl)ethyl]-N-[2-(5-bromopyridyl)]-thiourea::PETT deriv.

SMILES Brc1ccc(NC(=S)NCCc2nc3ccccc3[nH]2)nc1

InChI Key InChIKey=BZQJNJHZOGPJJO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 2155   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM2155(3-[2-(1H-1,3-benzodiazol-2-yl)ethyl]-1-(5-bromopyr...)
Affinity DataIC50:  21nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM2155(3-[2-(1H-1,3-benzodiazol-2-yl)ethyl]-1-(5-bromopyr...)
Affinity DataIC50:  1.86E+3nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1127,L687I]/[588-1147,L687I](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM2155(3-[2-(1H-1,3-benzodiazol-2-yl)ethyl]-1-(5-bromopyr...)
Affinity DataIC50: >2.50E+3nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed