BDBM21615 1-phenyl-1H-pyrazole-4-carboxylic acid::Pyrazole, 1

SMILES OC(=O)c1cnn(c1)-c1ccccc1

InChI Key InChIKey=ZROILLPDIUNLSE-UHFFFAOYSA-N

Data  1 IC50  1 Kd

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 21615   

TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM21615(1-phenyl-1H-pyrazole-4-carboxylic acid | Pyrazole,...)
Affinity DataKd:  1.40E+5nMAssay Description:Binding affinity to human HPGDS expressed in Escherichia coli by isothermal titration calorimetryMore data for this Ligand-Target Pair
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM21615(1-phenyl-1H-pyrazole-4-carboxylic acid | Pyrazole,...)
Affinity DataIC50:  8.90E+5nMpH: 7.2 T: 2°CAssay Description:The PGDS glutathione-S-transferase (GST) activity was measured by using MonoChloroBimane (MCB) as a chromogenic substrate. The assay was run at 384-w...More data for this Ligand-Target Pair