BDBM21658 (2S)-3-(1H-indol-3-yl)-2-[(2S)-3-sulfanyl-2-[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]propanamido]propanoic acid::Mercaptoacyl amino acid compound, 14c
SMILES OC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](CS)[C@H]1CCCc2ccccc12
InChI Key InChIKey=NEVHGNNWXYABCA-ONTIZHBOSA-N
Data 3 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 21658
Affinity DataKi: 3nM ΔG°: -12.1kcal/molepH: 7.4 T: 2°CAssay Description:NEP was preincubated in black 96-well microplates with or without increasing concentrations of inhibitors. DGPA was added, and the reaction was stopp...More data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Specific activity of ACE was assayed in black 96-well microplates with or without various concentrations of inhibitors. N-Cbz-Phe-His-Leu was added, ...More data for this Ligand-Target Pair
Affinity DataKi: 190nMAssay Description:ECE activity was performed in black 96-well microplates with recombinant human ECE-1c (hECE-1c). The hECE-1c was preincubated with or without increa...More data for this Ligand-Target Pair