BDBM22542 4-(1H-imidazol-4-ylmethyl)piperidine::4-(1H-imidazol-5-ylmethyl)piperidine::Immepip
SMILES C(C1CCNCC1)c1cnc[nH]1
InChI Key InChIKey=MCNGUYXRBCIGOV-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 19 hits for monomerid = 22542
Affinity DataKi: 0.300nMAssay Description:Displacement of [3H] (R)-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in CHO cells after 1 hr by liquid scintillation...More data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Displacement of [3H]-(R)-alpha-methylhistamine from human histamine H3 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from histamine H3 receptor in guinea pig brainMore data for this Ligand-Target Pair
Affinity DataKi: 0.407nM ΔG°: -12.8kcal/molepH: 7.4 T: 2°CAssay Description:Ligand displacement assays were performed on CHO cells membranes expressing hH3R. Retained radioactivity was determined by liquid scintillation count...More data for this Ligand-Target Pair
Affinity DataKi: 0.501nMAssay Description:Ligand displacement assays were performed on The SK-N-MC/hH3R cell homogenates. Retained radioactivity was determined by liquid scintillation countin...More data for this Ligand-Target Pair
Affinity DataKi: 0.501nMAssay Description:Displacement of [3H]histamine from human H3 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
TargetHistamine H4 receptor(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute
Curated by PDSP Ki Database
The R. W. Johnson Pharmaceutical Research Institute
Curated by PDSP Ki Database
TargetHistamine H4 receptor(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute
Curated by PDSP Ki Database
The R. W. Johnson Pharmaceutical Research Institute
Curated by PDSP Ki Database
Affinity DataKi: 19.9nMAssay Description:Displacement of [3H]histamine from human H4 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
TargetHistamine H4 receptor(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute
Curated by PDSP Ki Database
The R. W. Johnson Pharmaceutical Research Institute
Curated by PDSP Ki Database
Affinity DataKi: 20nMAssay Description:Ligand displacement assays were performed on The SK-N-MC/hH4R cell homogenates. Retained radioactivity was determined by liquid scintillation countin...More data for this Ligand-Target Pair
TargetHistamine H4 receptor(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute
Curated by PDSP Ki Database
The R. W. Johnson Pharmaceutical Research Institute
Curated by PDSP Ki Database
Affinity DataKi: 22nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in CHO-K1 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [125I]aminopotentidine from human histamine H2 receptor expressed in CHO-K1 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataEC50: 0.670nMAssay Description:Agonist activity at human recombinant histamine H3 receptor expressed in CHO-K1 cells assessed as [35S]GTPgammaS binding after 1 hr by liquid scintil...More data for this Ligand-Target Pair
TargetHistamine H4 receptor(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute
Curated by PDSP Ki Database
The R. W. Johnson Pharmaceutical Research Institute
Curated by PDSP Ki Database
Affinity DataEC50: 15.8nMAssay Description:Agonist activity at human histamine H4 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 0.670nMAssay Description:Agonist activity at human histamine H3 receptor expressed in CHO cells assessed as [35S]GTPgammaS bindingMore data for this Ligand-Target Pair