BDBM225955 FXR_45

SMILES CCOC(=O)c1ccc(NC(=O)c2c3CN(CCc3nn2-c2ccc(OC(F)(F)F)cc2)S(=O)(=O)c2cccs2)cc1

InChI Key InChIKey=CIINRYINLDSICD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 225955   

TargetBile acid receptor(Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM225955(FXR_45)
Affinity DataIC50:  2.89E+4nMpH: 7.4Assay Description:The assay buffer contained 50 mM HEPES (pH 7.4), 10 mM NaCl, 5 mM MgCl2 and 0.01% CHAPS. The reactions were incubated for 30 min in the presence of [...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed