BDBM225974 FXR_67

SMILES OC(=O)C[C@H]1CC[C@H](CC1)NC(=O)[C@H](C1CCCCC1)n1c(nc2cc(F)c(F)cc12)-c1ccc(nc1)-n1cccn1

InChI Key InChIKey=HDCRKZLZUYTUEN-JLDOJFOQSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 225974   

TargetBile acid receptor(Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM225974(FXR_67)
Affinity DataIC50:  3.31E+4nMpH: 7.4Assay Description:The assay buffer contained 50 mM HEPES (pH 7.4), 10 mM NaCl, 5 mM MgCl2 and 0.01% CHAPS. The reactions were incubated for 30 min in the presence of [...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed