BDBM228523 US9340555, F3

SMILES COC(=O)c1cc2nccc(Oc3cccc(NC(=O)Nc4cc(C)ccc4F)c3)c2s1

InChI Key InChIKey=SJMKELNHAJGCDT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 228523   

TargetVascular endothelial growth factor receptor 2(Human)
Allergan

US Patent
LigandPNGBDBM228523(US9340555, F3)
Affinity DataIC50: 21nMpH: 7.2 T: 2°CAssay Description:Kinase assays were performed in 96 well microtiter plates that were coated overnight with 30 μg of poly-Glu-Tyr (4:1) in 10 mM Phosphate Buffered ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2017
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Allergan

US Patent
LigandPNGBDBM228523(US9340555, F3)
Affinity DataIC50: 35nMT: 2°CAssay Description:Automated FLIPR (Fluorometric Imaging Plate Reader) technology was used to screen for inhibitors of VEGF induced increases in intracellular calcium l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2017
Entry Details
US Patent