BDBM22867 1,1-diethyl-3-[(8beta)-6-methyl-9,10-didehydroergolin-8-yl]urea::3,3-diethyl-1-[(4R,7R)-6-methyl-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca-1(15),2,9,12(16),13-pentaen-4-yl]urea::8R-lisuride::LISURIDE

SMILES: [H][C@@]12Cc3c[nH]c4cccc(C1=C[C@H](CN2C)NC(=O)N(CC)CC)c34

InChI Key: InChIKey=BKRGVLQUQGGVSM-UHFFFAOYSA-N

Data: 56 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 56 hits for monomerid = 22867   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-2A adrenergic receptor (Human)	BDBM22867 (3,3-diethyl-1-[(4R,7R)-6-methyl-6,11-diazatetracyc...) Show SMILES Show InChI	GoogleScholar	UniChem		0.0500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2B adrenergic receptor (Human)	BDBM22867 (3,3-diethyl-1-[(4R,7R)-6-methyl-6,11-diazatetracyc...) Show SMILES Show InChI	GoogleScholar	UniChem		0.130	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Human)	BDBM22867 (3,3-diethyl-1-[(4R,7R)-6-methyl-6,11-diazatetracyc...) Show SMILES Show InChI	GoogleScholar	UniChem		0.150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Human)	BDBM22867 (3,3-diethyl-1-[(4R,7R)-6-methyl-6,11-diazatetracyc...) Show SMILES Show InChI	GoogleScholar	UniChem		0.280	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Human)	BDBM22867 (3,3-diethyl-1-[(4R,7R)-6-methyl-6,11-diazatetracyc...) Show SMILES Show InChI	GoogleScholar	UniChem		0.340	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Human)	BDBM22867 (3,3-diethyl-1-[(4R,7R)-6-methyl-6,11-diazatetracyc...) Show SMILES Show InChI	GoogleScholar	UniChem		0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Human)	BDBM22867 (3,3-diethyl-1-[(4R,7R)-6-methyl-6,11-diazatetracyc...) Show SMILES Show InChI	GoogleScholar	UniChem		0.410	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Rat)	BDBM22867 (3,3-diethyl-1-[(4R,7R)-6-methyl-6,11-diazatetracyc...) Show SMILES Show InChI	GoogleScholar	UniChem		0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Rat)	BDBM22867 (3,3-diethyl-1-[(4R,7R)-6-methyl-6,11-diazatetracyc...) Show SMILES Show InChI	GoogleScholar	UniChem		0.520	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Rat)	BDBM22867 (3,3-diethyl-1-[(4R,7R)-6-methyl-6,11-diazatetracyc...) Show SMILES Show InChI	GoogleScholar	UniChem		0.520	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Human)	BDBM22867 (3,3-diethyl-1-[(4R,7R)-6-methyl-6,11-diazatetracyc...) Show SMILES Show InChI	GoogleScholar	UniChem		0.660	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM22867 (3,3-diethyl-1-[(4R,7R)-6-methyl-6,11-diazatetracyc...) Show SMILES Show InChI	GoogleScholar	UniChem		0.740	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465] (Rat)	BDBM22867 (3,3-diethyl-1-[(4R,7R)-6-methyl-6,11-diazatetracyc...) Show SMILES Show InChI	GoogleScholar	UniChem		0.790	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Rat)	BDBM22867 (3,3-diethyl-1-[(4R,7R)-6-methyl-6,11-diazatetracyc...) Show SMILES Show InChI	GoogleScholar	UniChem		0.890	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Rat)	BDBM22867 (3,3-diethyl-1-[(4R,7R)-6-methyl-6,11-diazatetracyc...) Show SMILES Show InChI	GoogleScholar	UniChem		0.890	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Human)	BDBM22867 (3,3-diethyl-1-[(4R,7R)-6-methyl-6,11-diazatetracyc...) Show SMILES Show InChI	GoogleScholar	UniChem		0.980	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Human)	BDBM22867 (3,3-diethyl-1-[(4R,7R)-6-methyl-6,11-diazatetracyc...) Show SMILES Show InChI	GoogleScholar	UniChem		1.07	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Human)	BDBM22867 (3,3-diethyl-1-[(4R,7R)-6-methyl-6,11-diazatetracyc...) Show SMILES Show InChI	GoogleScholar	UniChem		1.32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Human)	BDBM22867 (3,3-diethyl-1-[(4R,7R)-6-methyl-6,11-diazatetracyc...) Show SMILES Show InChI	GoogleScholar	UniChem		1.38	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM22867 (3,3-diethyl-1-[(4R,7R)-6-methyl-6,11-diazatetracyc...) Show SMILES Show InChI	GoogleScholar	UniChem		1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rat)	BDBM22867 (3,3-diethyl-1-[(4R,7R)-6-methyl-6,11-diazatetracyc...) Show SMILES Show InChI	GoogleScholar	UniChem		2.04	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM22867 (3,3-diethyl-1-[(4R,7R)-6-methyl-6,11-diazatetracyc...) Show SMILES Show InChI	GoogleScholar	UniChem		2.75	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Human)	BDBM22867 (3,3-diethyl-1-[(4R,7R)-6-methyl-6,11-diazatetracyc...) Show SMILES Show InChI	GoogleScholar	UniChem		2.95	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Guinea pig)	BDBM22867 (3,3-diethyl-1-[(4R,7R)-6-methyl-6,11-diazatetracyc...) Show SMILES Show InChI	GoogleScholar	UniChem		2.95	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Guinea pig)	BDBM22867 (3,3-diethyl-1-[(4R,7R)-6-methyl-6,11-diazatetracyc...) Show SMILES Show InChI	GoogleScholar	UniChem		3.16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(1B) dopamine receptor (Human)	BDBM22867 (3,3-diethyl-1-[(4R,7R)-6-methyl-6,11-diazatetracyc...) Show SMILES Show InChI	GoogleScholar	UniChem		3.55	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Human)	BDBM22867 (3,3-diethyl-1-[(4R,7R)-6-methyl-6,11-diazatetracyc...) Show SMILES Show InChI	GoogleScholar	UniChem		4.57	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Human)	BDBM22867 (3,3-diethyl-1-[(4R,7R)-6-methyl-6,11-diazatetracyc...) Show SMILES Show InChI	GoogleScholar	UniChem		4.74	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM22867 (3,3-diethyl-1-[(4R,7R)-6-methyl-6,11-diazatetracyc...) Show SMILES Show InChI	GoogleScholar	UniChem		5.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Rat)	BDBM22867 (3,3-diethyl-1-[(4R,7R)-6-methyl-6,11-diazatetracyc...) Show SMILES Show InChI	GoogleScholar	UniChem		5.24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Rat)	BDBM22867 (3,3-diethyl-1-[(4R,7R)-6-methyl-6,11-diazatetracyc...) Show SMILES Show InChI	GoogleScholar	UniChem		5.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rat)	BDBM22867 (3,3-diethyl-1-[(4R,7R)-6-methyl-6,11-diazatetracyc...) Show SMILES Show InChI	GoogleScholar	UniChem		5.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Human)	BDBM22867 (3,3-diethyl-1-[(4R,7R)-6-methyl-6,11-diazatetracyc...) Show SMILES Show InChI	GoogleScholar	UniChem		5.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Human)	BDBM22867 (3,3-diethyl-1-[(4R,7R)-6-methyl-6,11-diazatetracyc...) Show SMILES Show InChI	GoogleScholar	UniChem		5.88	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Rat)	BDBM22867 (3,3-diethyl-1-[(4R,7R)-6-methyl-6,11-diazatetracyc...) Show SMILES Show InChI	GoogleScholar	UniChem		6.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Rat)	BDBM22867 (3,3-diethyl-1-[(4R,7R)-6-methyl-6,11-diazatetracyc...) Show SMILES Show InChI	GoogleScholar	UniChem		6.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Rat)	BDBM22867 (3,3-diethyl-1-[(4R,7R)-6-methyl-6,11-diazatetracyc...) Show SMILES Show InChI	GoogleScholar	UniChem		6.31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Human)	BDBM22867 (3,3-diethyl-1-[(4R,7R)-6-methyl-6,11-diazatetracyc...) Show SMILES Show InChI	GoogleScholar	UniChem		6.46	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Human)	BDBM22867 (3,3-diethyl-1-[(4R,7R)-6-methyl-6,11-diazatetracyc...) Show SMILES Show InChI	GoogleScholar	UniChem		6.61	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Human)	BDBM22867 (3,3-diethyl-1-[(4R,7R)-6-methyl-6,11-diazatetracyc...) Show SMILES Show InChI	GoogleScholar	UniChem		6.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Human)	BDBM22867 (3,3-diethyl-1-[(4R,7R)-6-methyl-6,11-diazatetracyc...) Show SMILES Show InChI	GoogleScholar	UniChem		6.91	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Rat)	BDBM22867 (3,3-diethyl-1-[(4R,7R)-6-methyl-6,11-diazatetracyc...) Show SMILES Show InChI	GoogleScholar	UniChem		7.24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-2 adrenergic receptor (Human)	BDBM22867 (3,3-diethyl-1-[(4R,7R)-6-methyl-6,11-diazatetracyc...) Show SMILES Show InChI	GoogleScholar	UniChem		7.94	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Rat)	BDBM22867 (3,3-diethyl-1-[(4R,7R)-6-methyl-6,11-diazatetracyc...) Show SMILES Show InChI	GoogleScholar	UniChem		8.12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Rat)	BDBM22867 (3,3-diethyl-1-[(4R,7R)-6-methyl-6,11-diazatetracyc...) Show SMILES Show InChI	GoogleScholar	UniChem		8.19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rat)	BDBM22867 (3,3-diethyl-1-[(4R,7R)-6-methyl-6,11-diazatetracyc...) Show SMILES Show InChI	GoogleScholar	UniChem		11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rat)	BDBM22867 (3,3-diethyl-1-[(4R,7R)-6-methyl-6,11-diazatetracyc...) Show SMILES Show InChI	GoogleScholar	UniChem		15.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1B adrenergic receptor (Human)	BDBM22867 (3,3-diethyl-1-[(4R,7R)-6-methyl-6,11-diazatetracyc...) Show SMILES Show InChI	GoogleScholar	UniChem		16.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Human)	BDBM22867 (3,3-diethyl-1-[(4R,7R)-6-methyl-6,11-diazatetracyc...) Show SMILES Show InChI	GoogleScholar	UniChem		18.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 7 (Guinea pig)	BDBM22867 (3,3-diethyl-1-[(4R,7R)-6-methyl-6,11-diazatetracyc...) Show SMILES Show InChI	GoogleScholar	UniChem		18.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair