BDBM22876 CHEMBL998::Claritin::Loratadine::Sch 29851::US9138431, LORATADINE (Claritin)::US9333199, LORATADINE (Claritin)::ethyl 4-{13-chloro-4-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene}piperidine-1-carboxylate

SMILES: [#6]-[#6]-[#8]-[#6](=O)-[#7]-1-[#6]-[#6]\[#6](-[#6]-[#6]-1)=[#6]-1\c2ccc(Cl)cc2-[#6]-[#6]-c2cccnc-12

InChI Key: InChIKey=KJPJMTVTIDGCRM-UHFFFAOYSA-N

Data: 5 KI  26 IC50  1 Kd  4 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 36 hits for monomerid = 22876   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear receptor subfamily 1 group I member 2 (Human)	BDBM22876 (Sch 29851 | Claritin | CHEMBL998 | ethyl 4-{13-chl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM22876 (Sch 29851 | Claritin | CHEMBL998 | ethyl 4-{13-chl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM22876 (Sch 29851 | Claritin | CHEMBL998 | ethyl 4-{13-chl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	174	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM22876 (Sch 29851 | Claritin | CHEMBL998 | ethyl 4-{13-chl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	174	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-dependent translocase ABCB1 (Human)	BDBM22876 (Sch 29851 | Claritin | CHEMBL998 | ethyl 4-{13-chl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.14E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Nuclear receptor subfamily 1 group I member 2 (Human)	BDBM22876 (Sch 29851 | Claritin | CHEMBL998 | ethyl 4-{13-chl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a
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Bile acid receptor (Human)	BDBM22876 (Sch 29851 | Claritin | CHEMBL998 | ethyl 4-{13-chl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.07E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium-dependent neutral amino acid transporter B(0)AT2 (Human)	BDBM22876 (Sch 29851 | Claritin | CHEMBL998 | ethyl 4-{13-chl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Nuclear receptor subfamily 1 group I member 2 (Human)	BDBM22876 (Sch 29851 | Claritin | CHEMBL998 | ethyl 4-{13-chl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.26E+4	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM22876 (Sch 29851 | Claritin | CHEMBL998 | ethyl 4-{13-chl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
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Nuclear receptor subfamily 1 group I member 2 (Human)	BDBM22876 (Sch 29851 | Claritin | CHEMBL998 | ethyl 4-{13-chl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a
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Cytochrome P450 2C19 (Human)	BDBM22876 (Sch 29851 | Claritin | CHEMBL998 | ethyl 4-{13-chl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C8 (Human)	BDBM22876 (Sch 29851 | Claritin | CHEMBL998 | ethyl 4-{13-chl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.95E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2D6 (Human)	BDBM22876 (Sch 29851 | Claritin | CHEMBL998 | ethyl 4-{13-chl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM22876 (Sch 29851 | Claritin | CHEMBL998 | ethyl 4-{13-chl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C9 (Human)	BDBM22876 (Sch 29851 | Claritin | CHEMBL998 | ethyl 4-{13-chl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 1A2 (Human)	BDBM22876 (Sch 29851 | Claritin | CHEMBL998 | ethyl 4-{13-chl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium channel subfamily K member 9 (Human)	BDBM22876 (Sch 29851 | Claritin | CHEMBL998 | ethyl 4-{13-chl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.34E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H1 receptor (Human)	BDBM22876 (Sch 29851 | Claritin | CHEMBL998 | ethyl 4-{13-chl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.50E+6	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H1 receptor (Human)	BDBM22876 (Sch 29851 | Claritin | CHEMBL998 | ethyl 4-{13-chl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.50E+6	n/a	n/a	n/a	n/a	n/a	n/a
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Bile salt export pump (Human)	BDBM22876 (Sch 29851 | Claritin | CHEMBL998 | ethyl 4-{13-chl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 4 (Human)	BDBM22876 (Sch 29851 | Claritin | CHEMBL998 | ethyl 4-{13-chl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 3 (Human)	BDBM22876 (Sch 29851 | Claritin | CHEMBL998 | ethyl 4-{13-chl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 2 (Human)	BDBM22876 (Sch 29851 | Claritin | CHEMBL998 | ethyl 4-{13-chl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Platelet-activating factor receptor (Human)	BDBM22876 (Sch 29851 | Claritin | CHEMBL998 | ethyl 4-{13-chl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Voltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1F/alpha-1S (Human)	BDBM22876 (Sch 29851 | Claritin | CHEMBL998 | ethyl 4-{13-chl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.14E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Platelet-activating factor receptor (Human)	BDBM22876 (Sch 29851 | Claritin | CHEMBL998 | ethyl 4-{13-chl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.35E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H1 receptor (Human)	BDBM22876 (Sch 29851 | Claritin | CHEMBL998 | ethyl 4-{13-chl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM22876 (Sch 29851 | Claritin | CHEMBL998 | ethyl 4-{13-chl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM22876 (Sch 29851 | Claritin | CHEMBL998 | ethyl 4-{13-chl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	173	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H1 receptor (Human)	BDBM22876 (Sch 29851 | Claritin | CHEMBL998 | ethyl 4-{13-chl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H1 receptor (Human)	BDBM22876 (Sch 29851 | Claritin | CHEMBL998 | ethyl 4-{13-chl...) Show SMILES Show InChI	GoogleScholar	UniChem		37	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H1 receptor (Human)	BDBM22876 (Sch 29851 | Claritin | CHEMBL998 | ethyl 4-{13-chl...) Show SMILES Show InChI	GoogleScholar	UniChem		311	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H1 receptor (Rat)	BDBM22876 (Sch 29851 | Claritin | CHEMBL998 | ethyl 4-{13-chl...) Show SMILES Show InChI	GoogleScholar	UniChem		350	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H1 receptor (Human)	BDBM22876 (Sch 29851 | Claritin | CHEMBL998 | ethyl 4-{13-chl...) Show SMILES Show InChI	GoogleScholar	UniChem		414	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H4 receptor (Human)	BDBM22876 (Sch 29851 | Claritin | CHEMBL998 | ethyl 4-{13-chl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	>-7.09	n/a	n/a	n/a	n/a	n/a	7.4	37
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