BDBM2288 3-(benzenesulfinyl)-5-chloro-1H-indole-2-carboxamide::5Cl3PhS-2IndolCONH2 inhibitor 14

SMILES NC(=O)c1[nH]c2ccc(Cl)cc2c1S(=O)c1ccccc1

InChI Key InChIKey=KFQBSPAPUUVFBQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 2288   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandPNGBDBM2288(3-(benzenesulfinyl)-5-chloro-1H-indole-2-carboxami...)
Affinity DataIC50:  23nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandPNGBDBM2288(3-(benzenesulfinyl)-5-chloro-1H-indole-2-carboxami...)
Affinity DataIC50:  1.39E+3nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027,K690N]/[588-1147,K690N](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandPNGBDBM2288(3-(benzenesulfinyl)-5-chloro-1H-indole-2-carboxami...)
Affinity DataIC50:  2.76E+3nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed