BDBM22925 (8R)-3-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H,6H,7H,8H-imidazo[4,5-d][1,3]diazepin-8-ol::Covidarabine::Deoxycoformycin::Nipent::Pentostatin

SMILES: OC[C@H]1O[C@H](C[C@@H]1O)n1cnc2[C@H](O)CNC=Nc12

InChI Key: InChIKey=FPVKHBSQESCIEP-UHFFFAOYSA-N

Data: 13 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 22925   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bile salt export pump (Human)	BDBM22925 (Covidarabine | (8R)-3-[(2R,4S,5R)-4-hydroxy-5-(hyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Adenosine deaminase (Bovine)	BDBM22925 (Covidarabine | (8R)-3-[(2R,4S,5R)-4-hydroxy-5-(hyd...) Show SMILES Show InChI	GoogleScholar	UniChem		0.00100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Adenosine deaminase (Bovine)	BDBM22925 (Covidarabine | (8R)-3-[(2R,4S,5R)-4-hydroxy-5-(hyd...) Show SMILES Show InChI	GoogleScholar	UniChem		0.00100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Adenosine deaminase (Human)	BDBM22925 (Covidarabine | (8R)-3-[(2R,4S,5R)-4-hydroxy-5-(hyd...) Show SMILES Show InChI	GoogleScholar	UniChem		0.00250	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Adenosine deaminase (Bovine)	BDBM22925 (Covidarabine | (8R)-3-[(2R,4S,5R)-4-hydroxy-5-(hyd...) Show SMILES Show InChI	GoogleScholar	UniChem		0.00250	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Adenosine deaminase (Human)	BDBM22925 (Covidarabine | (8R)-3-[(2R,4S,5R)-4-hydroxy-5-(hyd...) Show SMILES Show InChI	GoogleScholar	UniChem		0.00300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Adenosine deaminase (Bovine)	BDBM22925 (Covidarabine | (8R)-3-[(2R,4S,5R)-4-hydroxy-5-(hyd...) Show SMILES Show InChI	GoogleScholar	UniChem		0.0100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Adenosine deaminase (Human)	BDBM22925 (Covidarabine | (8R)-3-[(2R,4S,5R)-4-hydroxy-5-(hyd...) Show SMILES Show InChI	GoogleScholar	UniChem		0.0260	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Adenosine deaminase (Human)	BDBM22925 (Covidarabine | (8R)-3-[(2R,4S,5R)-4-hydroxy-5-(hyd...) Show SMILES Show InChI	GoogleScholar	UniChem		0.0330	-14.1	n/a	n/a	n/a	n/a	n/a	7.4	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Adenosine deaminase (malaria parasite P. falciparum)	BDBM22925 (Covidarabine | (8R)-3-[(2R,4S,5R)-4-hydroxy-5-(hyd...) Show SMILES Show InChI	GoogleScholar	UniChem		0.0380	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Adenosine deaminase (Human)	BDBM22925 (Covidarabine | (8R)-3-[(2R,4S,5R)-4-hydroxy-5-(hyd...) Show SMILES Show InChI	GoogleScholar	UniChem		0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Adenosine deaminase (Human)	BDBM22925 (Covidarabine | (8R)-3-[(2R,4S,5R)-4-hydroxy-5-(hyd...) Show SMILES Show InChI	GoogleScholar	UniChem		0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Adenosine deaminase (malaria parasite P. falciparum)	BDBM22925 (Covidarabine | (8R)-3-[(2R,4S,5R)-4-hydroxy-5-(hyd...) Show SMILES Show InChI	GoogleScholar	UniChem		8.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Adenosine deaminase (Human)	BDBM22925 (Covidarabine | (8R)-3-[(2R,4S,5R)-4-hydroxy-5-(hyd...) Show SMILES Show InChI	GoogleScholar	UniChem		1.19E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair