BDBM233547 US9353061, Lova-HA (1)

SMILES CCC(C)C(=O)OC1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H](O)C[C@@H](O)CC(=O)NO)[C@@H]12

InChI Key InChIKey=UZLJJCAWULBGEN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 233547   

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Human)
National Taiwan University

US Patent
LigandPNGBDBM233547(US9353061, Lova-HA (1))
Affinity DataIC50: 16.8nMpH: 7.4Assay Description:The HMGR activity was performed using HMG-CoA reductase assay kit from Sigma-Aldrich with the human recombinant protein or 100 μg total cell lys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
National Taiwan University

US Patent
LigandPNGBDBM233547(US9353061, Lova-HA (1))
Affinity DataIC50: 50.5nMT: 2°CAssay Description:The HDAC activity was performed using the HDAC fluorescent activity assay kit (BIOMOL, Plymouth Meeting, Pa., USA) according to the manufacturer'...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
National Taiwan University

US Patent
LigandPNGBDBM233547(US9353061, Lova-HA (1))
Affinity DataIC50: 60.1nMT: 2°CAssay Description:The HDAC activity was performed using the HDAC fluorescent activity assay kit (BIOMOL, Plymouth Meeting, Pa., USA) according to the manufacturer'...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetHistone deacetylase 2(Human)
National Taiwan University

US Patent
LigandPNGBDBM233547(US9353061, Lova-HA (1))
Affinity DataIC50: 468nMT: 2°CAssay Description:The HDAC activity was performed using the HDAC fluorescent activity assay kit (BIOMOL, Plymouth Meeting, Pa., USA) according to the manufacturer'...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent