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Enter Data

BDBM238361 3-(4-Methoxyphenyl)-4-cyano-5-(isopropylthio)thiophene-2-carboxylic acid (1j)

SMILES: COc1ccc(cc1)-c1c(sc(SC(C)C)c1C#N)C(O)=O

InChI Key: InChIKey=IPQWKNOXOTZXOP-UHFFFAOYSA-N

Data: 3 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 238361
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Baker's yeast)	BDBM238361 (3-(4-Methoxyphenyl)-4-cyano-5-(isopropylthio)thiop...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	250	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Human)	BDBM238361 (3-(4-Methoxyphenyl)-4-cyano-5-(isopropylthio)thiop...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Protein farnesyltransferase alpha subunit/subunit beta (Trypanosoma brucei brucei)	BDBM238361 (3-(4-Methoxyphenyl)-4-cyano-5-(isopropylthio)thiop...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair