BDBM239660 US9394309, 116

SMILES Cc1cc(C)c(cc1NC(=O)c1cc(nc(c1)C(C)(C)C)C#N)-n1ccn2nc(cc12)-c1cccnc1

InChI Key InChIKey=VERMPDFSSGPKSK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 239660   

TargetAngiopoietin-1 receptor [776-1124](Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM239660(US9394309, 116)
Affinity DataIC50:  2.90nMpH: 9.6 T: 2°CAssay Description:For measuring the autophosphorylation of the endogenous Tie2 receptor in the cell lysates prepared, a self-prepared anti-Tie2 antibody directed again...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAngiopoietin-1 receptor [776-1124](Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM239660(US9394309, 116)
Affinity DataIC50:  0.5nMpH: 7.0 T: 2°CAssay Description:For the assay, 50 nl of a 100-fold concentrated solution of the respective test substance in DMSO were pipetted into a black low-volume 384-well micr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent