BDBM24135 7-bromo-4-(3-hydroxyphenyl)-N,N-dimethyl-1,2,3,4-tetrahydroisoquinoline-2-carboxamide::CHEMBL438800::tetrahydroisoquinoline (THIQ), 39

SMILES CN(C)C(=O)N1CC(c2cccc(O)c2)c2ccc(Br)cc2C1

InChI Key InChIKey=QGJPPNDXBDCENW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 24135   

TargetKinesin-like protein KIF11(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM24135(7-bromo-4-(3-hydroxyphenyl)-N,N-dimethyl-1,2,3,4-t...)
Affinity DataIC50:  808nMAssay Description:Inhibition of KSPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM24135(7-bromo-4-(3-hydroxyphenyl)-N,N-dimethyl-1,2,3,4-t...)
Affinity DataIC50:  808nMAssay Description:ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed