BDBM241822 US9416123, 3a

SMILES Clc1cc(Cl)c(N\N=C\c2ccncc2)c(Cl)c1

InChI Key InChIKey=RNCOCKWSMNQPJZ-REZTVBANSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 241822   

TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Synovo

US Patent
LigandPNGBDBM241822(US9416123, 3a)
Affinity DataIC50:  2.00E+3nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Synovo

US Patent
LigandPNGBDBM241822(US9416123, 3a)
Affinity DataIC50:  2.50E+3nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Synovo

US Patent
LigandPNGBDBM241822(US9416123, 3a)
Affinity DataIC50:  210nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
In DepthDetails US Patent