BDBM243997 (s)-n-(2-hydroxy-1-phenylethyl)-5,5-dimethyl-2-((1-methyl-1h-pyrazol-3-yl)amino)-5h-pyrrolo[3,4-d]pyrimidine-6(7h)-carboxamide::US9546173, cmpd 71

SMILES Cn1ccc(Nc2ncc3c(CN(C(=O)N[C@H](CO)c4ccccc4)C3(C)C)n2)n1

InChI Key InChIKey=LARAUDMILHNNRM-QGZVFWFLSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 243997   

TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM243997((s)-n-(2-hydroxy-1-phenylethyl)-5,5-dimethyl-2-((1...)
Affinity DataIC50:  2.55E+3nMpH: 7.5Assay Description:Compound potency against activated ERK2 was determined using a kinase assay that measures ERK2-catalyzed phosphorylation of biotinylated ERKtide pept...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent