BDBM244025 9-((5-chloro-4-(2-(isopropylsulfonyl)phenyl)aminopyrimidin-2-yl)amino)-10-methoxy-2,3,6,7-tetrahydro-1H-pyrazino[2,1-a]isoquinoline)-4(11bH)-one::US10053458, 84
SMILES COc1cc2C3CNCC(=O)N3CCc2cc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1
InChI Key InChIKey=XJMFPTCMAYQIDJ-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 244025
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: <10nMT: 2°CAssay Description:A proliferation inhibitory activity against the ALK of the compound represented by Chemical Formula 1 according to the present invention at an enzyme...More data for this Ligand-Target Pair
Affinity DataIC50: 2.80nMAssay Description:Inhibition of insulin receptor kinase (unknown origin) using TK as substrate after 30 mins by HTRF assayMore data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 3.70nMAssay Description:Inhibition of wild type ALK (unknown origin) using TK as substrate after 30 mins by HTRF assayMore data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent