BDBM244079 US9428478, TG6-205-2

SMILES Oc1ccc2[nH]c(cc2c1)C(=O)N1CCN(CC1)c1ccc(OC(F)(F)F)cc1

InChI Key InChIKey=DZTLMHZPDFJUAT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 244079   

TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
Emory University

US Patent
LigandPNGBDBM244079(US9428478, TG6-205-2)
Affinity DataIC50:  2.00E+8nMAssay Description:Assay controls. To rule out interference with either Nox2 or Nox4 luminescence assays, two approaches are used. In one, xanthine oxidase replaces the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome b-245 heavy chain(Homo sapiens (Human))
Emory University

US Patent
LigandPNGBDBM244079(US9428478, TG6-205-2)
Affinity DataIC50:  1.50E+9nMAssay Description:Nox2 activity assay for primary screening: Plasma membranes were prepared from human neutrophils, which express large amounts of Nox2, stored at W...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent