BDBM244212 (5,5-dimethyl-2-(phenylamino)-5h-pyrrolo[3,4-d]pyrimidin-6(7h)-yl)(4-methylpiperazin-1-yl)methanone::US9546173, cmpd 151

SMILES: CN1CCN(CC1)C(=O)N1Cc2nc(Nc3ccccc3)ncc2C1(C)C

InChI Key: InChIKey=FLSBFSZAHVORFU-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 244212   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 1 (Human)	BDBM244212 ((5,5-dimethyl-2-(phenylamino)-5h-pyrrolo[3,4-d]pyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.57E+3	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-1 (Human)	BDBM244212 ((5,5-dimethyl-2-(phenylamino)-5h-pyrrolo[3,4-d]pyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.61E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 (Human)	BDBM244212 ((5,5-dimethyl-2-(phenylamino)-5h-pyrrolo[3,4-d]pyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.17E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair