BDBM244214 5,5-dimethyl-n-(1-methylazetidin-3-yl)-2-(phenylamino)-5h-pyrrolo[3,4-d]pyrimidine-6(7h)-carboxamide::US9546173, cmpd 153

SMILES CN1CC(C1)NC(=O)N1Cc2nc(Nc3ccccc3)ncc2C1(C)C

InChI Key InChIKey=BYXHFKCDIPWWBC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 244214   

TargetRibosomal protein S6 kinase alpha-3(Human)
Novartis

US Patent
LigandPNGBDBM244214(5,5-dimethyl-n-(1-methylazetidin-3-yl)-2-(phenylam...)
Affinity DataIC50: 1.37E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Novartis

US Patent
LigandPNGBDBM244214(5,5-dimethyl-n-(1-methylazetidin-3-yl)-2-(phenylam...)
Affinity DataIC50: 1.25E+5nMpH: 7.5Assay Description:Compound potency against activated ERK2 was determined using a kinase assay that measures ERK2-catalyzed phosphorylation of biotinylated ERKtide pept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2018
Entry Details
US Patent