BDBM244242 5,5-dimethyl-n-(oxazol-4-ylmethyl)-2-(phenylamino)-5h-pyrrolo[3,4-d]pyrimidine-6(7h)-carboxamide::US9546173, cmpd 162

SMILES CC1(C)N(Cc2nc(Nc3ccccc3)ncc12)C(=O)NCc1cocn1

InChI Key InChIKey=PUGSSBKEKJKQGE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 244242   

TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM244242(5,5-dimethyl-n-(oxazol-4-ylmethyl)-2-(phenylamino)...)
Affinity DataIC50:  8.21E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM244242(5,5-dimethyl-n-(oxazol-4-ylmethyl)-2-(phenylamino)...)
Affinity DataIC50:  1.62E+4nMpH: 7.5Assay Description:Compound potency against activated ERK2 was determined using a kinase assay that measures ERK2-catalyzed phosphorylation of biotinylated ERKtide pept...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent