BDBM246896 4-chloro-3'-fluoro-3- methyl-6-[1-(9H-purin-6- ylamino)ethyl]biphenyl- 2-carbonitrile::US10053465, 34::US10065963, Compound 34::US10675284, Example 34::US11136326, Example 34++

SMILES: CC(Nc1ncnc2[nH]cnc12)c1cc(Cl)c(C)c(C#N)c1-c1cccc(F)c1

InChI Key: InChIKey=IEXWGFFVZUJNEK-UHFFFAOYSA-N

Data: 9 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 246896   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Human)	BDBM246896 (4-chloro-3'-fluoro-3- methyl-6-[1-(9H-purin-6-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	75	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Mer (Human)	BDBM246896 (4-chloro-3'-fluoro-3- methyl-6-[1-(9H-purin-6-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor UFO (Human)	BDBM246896 (4-chloro-3'-fluoro-3- methyl-6-[1-(9H-purin-6-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	25
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Tyrosine-protein kinase receptor TYRO3 (Human)	BDBM246896 (4-chloro-3'-fluoro-3- methyl-6-[1-(9H-purin-6-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a	n/a	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Human)	BDBM246896 (4-chloro-3'-fluoro-3- methyl-6-[1-(9H-purin-6-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	75	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Human)	BDBM246896 (4-chloro-3'-fluoro-3- methyl-6-[1-(9H-purin-6-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<2.00E+3	n/a	n/a	n/a	n/a	6.7	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Human)	BDBM246896 (4-chloro-3'-fluoro-3- methyl-6-[1-(9H-purin-6-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	75	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Human)	BDBM246896 (4-chloro-3'-fluoro-3- methyl-6-[1-(9H-purin-6-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	75	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Human)	BDBM246896 (4-chloro-3'-fluoro-3- methyl-6-[1-(9H-purin-6-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	99	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair