BDBM24712 5-ethyl-7,7-dimethyl-2-(5-methyl-1H-pyrazol-3-yl)-1H,5H,6H,7H-imidazo[4,5-f]indol-6-one::Lactam analogue, 2

SMILES CCN1C(=O)C(C)(C)c2cc3nc([nH]c3cc12)-c1cc(C)[nH]n1

InChI Key InChIKey=QRFIOQPCVMNZPT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 24712   

TargetAurora kinase B(Homo sapiens (Human))
Genentech

LigandPNGBDBM24712(5-ethyl-7,7-dimethyl-2-(5-methyl-1H-pyrazol-3-yl)-...)
Affinity DataIC50:  130nMpH: 7.5 T: 2°CAssay Description:Aurora kinase was assayed in ELISA format using a GST fusion of the N-terminus of Histone H3 as substrate. Plates were coated with substrate, and the...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Genentech

LigandPNGBDBM24712(5-ethyl-7,7-dimethyl-2-(5-methyl-1H-pyrazol-3-yl)-...)
Affinity DataIC50:  69nMpH: 7.5 T: 2°CAssay Description:Aurora kinase was assayed in ELISA format using a GST fusion of the N-terminus of Histone H3 as substrate. Plates were coated with substrate, and the...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed