BDBM2481 5-Chloro-3-[(4-methylphenyl)sulfonyl]-1H-indole-2-carboxyamide::5-chloro-3-[(4-methylbenzene)sulfonyl]-1H-indole-2-carboxamide::Indolyl Aryl Sulfone 74

SMILES Cc1ccc(cc1)S(=O)(=O)c1c([nH]c2ccc(Cl)cc12)C(N)=O

InChI Key InChIKey=ISDVLXGUCZEBAA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 2481   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Sapienza University Of Rome

LigandPNGBDBM2481(5-Chloro-3-[(4-methylphenyl)sulfonyl]-1H-indole-2-...)
Affinity DataIC50:  72nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C](Human immunodeficiency virus type 1)
Sapienza University Of Rome

LigandPNGBDBM2481(5-Chloro-3-[(4-methylphenyl)sulfonyl]-1H-indole-2-...)
Affinity DataIC50:  110nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027,K690N]/[588-1147,K690N](Human immunodeficiency virus type 1)
Sapienza University Of Rome

LigandPNGBDBM2481(5-Chloro-3-[(4-methylphenyl)sulfonyl]-1H-indole-2-...)
Affinity DataIC50: >5.00E+3nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed