BDBM24999 4-[7-(3-aminopropoxy)-1-ethyl-4-(furan-3-yl)-1H-imidazo[4,5-c]pyridin-2-yl]-1,2,5-oxadiazol-3-amine::oxadiazole-containing compound, 11b

SMILES CCn1c(nc2c(ncc(OCCCN)c12)-c1ccoc1)-c1nonc1N

InChI Key InChIKey=SXRCGQAHDJRHJC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 24999   

TargetRibosomal protein S6 kinase alpha-1(Human)
Glaxosmithkline

LigandPNGBDBM24999(4-[7-(3-aminopropoxy)-1-ethyl-4-(furan-3-yl)-1H-im...)
Affinity DataIC50: 71nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from radiolabeled AT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2008
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Glaxosmithkline

LigandPNGBDBM24999(4-[7-(3-aminopropoxy)-1-ethyl-4-(furan-3-yl)-1H-im...)
Affinity DataIC50: 79nMpH: 7.5 T: 2°CAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from radiolabeled AT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2008
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase alpha-5(Human)
Glaxosmithkline

LigandPNGBDBM24999(4-[7-(3-aminopropoxy)-1-ethyl-4-(furan-3-yl)-1H-im...)
Affinity DataIC50: 162nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from radiolabeled AT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2008
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Glaxosmithkline

LigandPNGBDBM24999(4-[7-(3-aminopropoxy)-1-ethyl-4-(furan-3-yl)-1H-im...)
Affinity DataIC50: 562nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from radiolabeled AT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2008
Entry Details Article
PubMed