BDBM252362 US9458113, 6::US9458113, 7a

SMILES CN1C(C2=C(CCCC2=O)N(C1=O)c1cccc(c1)C(F)(F)F)c1ccc(cc1C(N)=O)C#N

InChI Key InChIKey=FZRNGZMJAHANSY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 252362   

TargetNeutrophil elastase(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM252362(US9458113, 6 | US9458113, 7a)
Affinity DataIC50: <1nMpH: 7.5 T: 2°CAssay Description:The following buffers were used: Compound buffer: 100 mM Tris, 500 mM NaCl, adjusted to pH 7.5; Assay buffer: 100 mM Tris, 500 mM NaCl, adjusted to p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeutrophil elastase(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM252362(US9458113, 6 | US9458113, 7a)
Affinity DataIC50:  1.60nMpH: 7.5 T: 2°CAssay Description:The following buffers were used: Compound buffer: 100 mM Tris, 500 mM NaCl, adjusted to pH 7.5; Assay buffer: 100 mM Tris, 500 mM NaCl, adjusted to p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent