BDBM25525 24-methyl-5,7,18,20-tetraoxa-24-azahexacyclo[11.11.0.0^{2,10}.0^{4,8}.0^{14,22}.0^{17,21}]tetracosa-1(13),2,4(8),9,11,14(22),15,17(21),23-nonaen-24-ium::CHEMBL490129::Pseudochelerythrine::Veadent::cid_5154::sanguinarine::sangvinarin

SMILES: C[n+]1cc2c(ccc3c2OCO3)c4c1c5cc6c(cc5cc4)OCO6

InChI Key: InChIKey=INVGWHRKADIJHF-UHFFFAOYSA-N

Data: 17 IC50  1 Kd

PDB links: 6 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 19 hits for monomerid = 25525   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA ligase 1 (Human)	BDBM25525 (CHEMBL490129 | 24-methyl-5,7,18,20-tetraoxa-24-aza...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.82E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Aromatic-L-amino-acid decarboxylase (Human)	BDBM25525 (CHEMBL490129 | 24-methyl-5,7,18,20-tetraoxa-24-aza...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Ras-related C3 botulinum toxin substrate 1 (Human)	BDBM25525 (CHEMBL490129 | 24-methyl-5,7,18,20-tetraoxa-24-aza...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cell division control protein 42 homolog (Human)	BDBM25525 (CHEMBL490129 | 24-methyl-5,7,18,20-tetraoxa-24-aza...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Transient receptor potential cation channel subfamily A member 1 (Human)	BDBM25525 (CHEMBL490129 | 24-methyl-5,7,18,20-tetraoxa-24-aza...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	90	n/a	n/a	n/a	n/a
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Cell division protein FtsZ (Escherichia coli (strain K12))	BDBM25525 (CHEMBL490129 | 24-methyl-5,7,18,20-tetraoxa-24-aza...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cell division protein FtsZ (Bacillus subtilis)	BDBM25525 (CHEMBL490129 | 24-methyl-5,7,18,20-tetraoxa-24-aza...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cell division protein FtsZ (Escherichia coli (strain K12))	BDBM25525 (CHEMBL490129 | 24-methyl-5,7,18,20-tetraoxa-24-aza...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.38E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cholinesterase (Human)	BDBM25525 (CHEMBL490129 | 24-methyl-5,7,18,20-tetraoxa-24-aza...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.08E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Acetylcholinesterase (Human)	BDBM25525 (CHEMBL490129 | 24-methyl-5,7,18,20-tetraoxa-24-aza...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.22E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Bcl-2-like protein 1 (Human)	BDBM25525 (CHEMBL490129 | 24-methyl-5,7,18,20-tetraoxa-24-aza...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a	8.0	22
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Reverse transcriptase (Human immunodeficiency virus type 1)	BDBM25525 (CHEMBL490129 | 24-methyl-5,7,18,20-tetraoxa-24-aza...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<4.51E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Regulator of G-protein signaling 17 (Human)	BDBM25525 (CHEMBL490129 | 24-methyl-5,7,18,20-tetraoxa-24-aza...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Regulator of G-protein signaling 17 (Human)	BDBM25525 (CHEMBL490129 | 24-methyl-5,7,18,20-tetraoxa-24-aza...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.28E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Regulator of G-protein signaling 17 (Human)	BDBM25525 (CHEMBL490129 | 24-methyl-5,7,18,20-tetraoxa-24-aza...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Regulator of G-protein signaling 17 (Human)	BDBM25525 (CHEMBL490129 | 24-methyl-5,7,18,20-tetraoxa-24-aza...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a
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Fibrinogen beta chain [164-491] (Human)	BDBM25525 (CHEMBL490129 | 24-methyl-5,7,18,20-tetraoxa-24-aza...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.31E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Fibrinogen beta chain [164-491] (Human)	BDBM25525 (CHEMBL490129 | 24-methyl-5,7,18,20-tetraoxa-24-aza...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.42E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Group 3 secretory phospholipase A2 (Human)	BDBM25525 (CHEMBL490129 | 24-methyl-5,7,18,20-tetraoxa-24-aza...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.18E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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