BDBM25918 2-(hydrazinecarbonyl)-3-(2,3,4,5,6-pentafluorophenyl)-1H-indole-5-sulfonamide::BMC173212 Compound 2n::indole sulfonamide, 8n

SMILES NNC(=O)c1[nH]c2ccc(cc2c1-c1c(F)c(F)c(F)c(F)c1F)S(N)(=O)=O

InChI Key InChIKey=AWDKBDAWOHYQRV-UHFFFAOYSA-N

Data  14 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 25918   

TargetCarbonic anhydrase 2(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM25918(2-(hydrazinecarbonyl)-3-(2,3,4,5,6-pentafluorophen...)
Affinity DataKi:  7nM ΔG°:  -11.1kcal/molepH: 7.4 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM25918(2-(hydrazinecarbonyl)-3-(2,3,4,5,6-pentafluorophen...)
Affinity DataKi:  8.70nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 15 [19-324](Mus musculus (mouse))
Istanbul University

LigandPNGBDBM25918(2-(hydrazinecarbonyl)-3-(2,3,4,5,6-pentafluorophen...)
Affinity DataKi:  48nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 7(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM25918(2-(hydrazinecarbonyl)-3-(2,3,4,5,6-pentafluorophen...)
Affinity DataKi:  68nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM25918(2-(hydrazinecarbonyl)-3-(2,3,4,5,6-pentafluorophen...)
Affinity DataKi:  70nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM25918(2-(hydrazinecarbonyl)-3-(2,3,4,5,6-pentafluorophen...)
Affinity DataKi:  79nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM25918(2-(hydrazinecarbonyl)-3-(2,3,4,5,6-pentafluorophen...)
Affinity DataKi:  110nM ΔG°:  -9.49kcal/molepH: 7.4 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-carbonic anhydrase domain-containing protein(Caenorhabditis elegans)
Istanbul University

LigandPNGBDBM25918(2-(hydrazinecarbonyl)-3-(2,3,4,5,6-pentafluorophen...)
Affinity DataKi:  260nM ΔG°:  -8.98kcal/molepH: 7.4 T: 2°CAssay Description:An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes. Phenol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 13(Mus musculus (mouse))
Istanbul University

LigandPNGBDBM25918(2-(hydrazinecarbonyl)-3-(2,3,4,5,6-pentafluorophen...)
Affinity DataKi:  734nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 5A, mitochondrial(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM25918(2-(hydrazinecarbonyl)-3-(2,3,4,5,6-pentafluorophen...)
Affinity DataKi:  750nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 5B, mitochondrial(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM25918(2-(hydrazinecarbonyl)-3-(2,3,4,5,6-pentafluorophen...)
Affinity DataKi:  862nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM25918(2-(hydrazinecarbonyl)-3-(2,3,4,5,6-pentafluorophen...)
Affinity DataKi:  5.22E+3nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM25918(2-(hydrazinecarbonyl)-3-(2,3,4,5,6-pentafluorophen...)
Affinity DataKi:  5.62E+3nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 3(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM25918(2-(hydrazinecarbonyl)-3-(2,3,4,5,6-pentafluorophen...)
Affinity DataKi:  5.40E+6nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed