BDBM26544 (3S)-1-{[4-(but-2-yn-1-yloxy)benzene]sulfonyl}pyrrolidine-3-thiol::thiol-arylsulfonamide, 4c

SMILES CC#CCOc1ccc(cc1)S(=O)(=O)N1CC[C@H](S)C1

InChI Key InChIKey=BLIQFUCBRCDFAI-ZDUSSCGKSA-N

Data  1 KI

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 26544   

LigandPNGBDBM26544((3S)-1-{[4-(but-2-yn-1-yloxy)benzene]sulfonyl}pyrr...)
Affinity DataKi:  33nM ΔG°:  -10.1kcal/molepH: 7.5 T: 2°CAssay Description:The compounds were tested for TACE inhibition using fluorescence resonance energy transfer (FRET) assay. TACE catalyzed cleavage of the substrate pep...More data for this Ligand-Target Pair