BDBM268623 US9718825, Example 20::US9718825, Example 22

SMILES O=S(=O)(Nc1ccc(-c2nc(NCc3cccnc3)c3cn[nH]c3n2)cc1)c1cc(Cl)ccc1F

InChI Key InChIKey=MBZADYOZAIAHPR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 268623   

TargetSerine/threonine-protein kinase Sgk1(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 268623BDBM268623(US9718825, Example 22 | US9718825, Example 20)
Affinity DataIC50: 39nMpH: 7.4Assay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2018
Entry Details
US Patent

TargetSerine/threonine-protein kinase Sgk1(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 268623BDBM268623(US9718825, Example 22 | US9718825, Example 20)
Affinity DataIC50: 80nMpH: 7.4Assay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2018
Entry Details
US Patent