BDBM268623 US9718825, Example 20::US9718825, Example 22

SMILES Fc1ccc(Cl)cc1S(=O)(=O)Nc1ccc(cc1)-c1nc(NCc2cccnc2)c2cn[nH]c2n1

InChI Key InChIKey=MBZADYOZAIAHPR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 268623   

TargetSerine/threonine-protein kinase Sgk1(Human)
Sanofi

US Patent
LigandPNGBDBM268623(US9718825, Example 22 | US9718825, Example 20)
Affinity DataIC50: 39nMpH: 7.4Assay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2018
Entry Details
US Patent

TargetSerine/threonine-protein kinase Sgk1(Human)
Sanofi

US Patent
LigandPNGBDBM268623(US9718825, Example 22 | US9718825, Example 20)
Affinity DataIC50: 80nMpH: 7.4Assay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2018
Entry Details
US Patent