BDBM268953 US9718825, Example 379

SMILES COc1ccc(F)c(c1)S(=O)(=O)Nc1ccc(cc1)-c1nc(OCCCO)c2c(C)n[nH]c2n1

InChI Key InChIKey=QDFGDKRMESNUTE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 268953   

TargetSerine/threonine-protein kinase Sgk1(Human)
Sanofi

US Patent
LigandPNGBDBM268953(US9718825, Example 379)
Affinity DataIC50: 2.80nMpH: 7.4Assay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2018
Entry Details
US Patent