BindingDB PrimarySearch_ki

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BDBM277605 US10072026, Example 6-24

SMILES: COc1cnc2cc(Nc3cc(C)[nH]n3)nc(N[C@H]3C[C@@H]4CC[C@H](C3)N4Cc3ccncc3)c2c1

InChI Key: InChIKey=MGMNFBWAMZYDCK-UHFFFAOYSA-N

Data: 4 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 277605
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Tyrosine-protein kinase JAK1 (Human)	BDBM277605 (US10072026, Example 6-24) Show SMILES Show InChI	GoogleScholar	UniChem		0.550	n/a	n/a	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Human)	BDBM277605 (US10072026, Example 6-24) Show SMILES Show InChI	GoogleScholar	UniChem		0.550	n/a	n/a	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Human)	BDBM277605 (US10072026, Example 6-24) Show SMILES Show InChI	GoogleScholar	UniChem		50	n/a	n/a	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Human)	BDBM277605 (US10072026, Example 6-24) Show SMILES Show InChI	GoogleScholar	UniChem		50	n/a	n/a	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair