BDBM282900 6-(4-(3-Chlorophenyl)-2-methyl-1H-imidazol-5- yl)quinoline::US10287295, Example 105::US11352360, Example 105::US9884868, Example 105

SMILES Cc1nc(c([nH]1)-c1ccc2ncccc2c1)-c1cccc(Cl)c1

InChI Key InChIKey=UFWWTBXPJRUJSU-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 282900   

TargetTGF-beta receptor type-1(Homo sapiens (Human))
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM282900(6-(4-(3-Chlorophenyl)-2-methyl-1H-imidazol-5- yl)q...)
Affinity DataIC50:  0.900nMpH: 7.4 T: 2°CAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTGF-beta receptor type-2(Homo sapiens (Human))
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM282900(6-(4-(3-Chlorophenyl)-2-methyl-1H-imidazol-5- yl)q...)
Affinity DataIC50:  2.93E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTGF-beta receptor type-2(Homo sapiens (Human))
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM282900(6-(4-(3-Chlorophenyl)-2-methyl-1H-imidazol-5- yl)q...)
Affinity DataIC50:  2.93E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTGF-beta receptor type-2(Homo sapiens (Human))
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM282900(6-(4-(3-Chlorophenyl)-2-methyl-1H-imidazol-5- yl)q...)
Affinity DataIC50:  2.93E+3nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM282900(6-(4-(3-Chlorophenyl)-2-methyl-1H-imidazol-5- yl)q...)
Affinity DataIC50:  0.900nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTGF-beta receptor type-1 [T204D](Homo sapiens (Human))
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM282900(6-(4-(3-Chlorophenyl)-2-methyl-1H-imidazol-5- yl)q...)
Affinity DataIC50:  0.900nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGF-βR1 T204D or...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent