BDBM282910 6-(4-(3-chloro-4-fluorophenyl)-1-(3,3,3- trifluoropropyl)-1H-imidazol-5-yl)imidazo[1,2- b]pyridazine-3-carboxamide::US9884868, Example 115'

SMILES: CCc1nc(c([nH]1)-c1ccc2ncnn2c1)-c1cccc(C)c1

InChI Key: InChIKey=QRRYAIVGAHXSHB-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 282910   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
TGF-beta receptor type-1 (Human)	BDBM282910 (6-(4-(3-chloro-4-fluorophenyl)-1-(3,3,3- trifluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.60	n/a	n/a	n/a	n/a	7.4	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
TGF-beta receptor type-2 (Human)	BDBM282910 (6-(4-(3-chloro-4-fluorophenyl)-1-(3,3,3- trifluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair