BDBM28429 (2R,3R,4S,5R)-2-(6-amino-8-ethyl-9H-purin-9-yl)-5-({[4-(aminooxy)butyl](methyl)amino}methyl)oxolane-3,4-diol::AdoMet substrate analogue, 14e

SMILES CCc1nc2c(N)ncnc2n1[C@@H]1O[C@H](CN(C)CCCCON)[C@@H](O)[C@H]1O

InChI Key InChIKey=HCBAQADKJBDTHF-IWCJZZDYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 28429   

TargetS-adenosylmethionine decarboxylase proenzyme(Homo sapiens (Human))
Cornell University

LigandPNGBDBM28429((2R,3R,4S,5R)-2-(6-amino-8-ethyl-9H-purin-9-yl)-5-...)
Affinity DataIC50:  15nMpH: 6.8 T: 2°CAssay Description:The C-terminal his-tagged AdoMetDC was assayed by measuring the release of 14CO2 from S-adenosyl-L-[carboxy-14C]methionine (Amersham Pharmacia Biotec...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed