BDBM284888 N-(5-{4-amino-7-[1-(1,1-dioxo-1lambda6- thian-4-yl)-1H-indazol-6-yl]pyrrolo [2,1-f][1,2,4]triazin-5-yl}pyridin-2- yl)acetamide::US10023576, Example 79

SMILES CC(=O)Nc1ccc(cn1)-c1cc(-c2ccc3cnn(C4CCS(=O)(=O)CC4)c3c2)n2ncnc(N)c12

InChI Key InChIKey=WGNBYXDJSFWVJN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 284888   

LigandChemical structure of BindingDB Monomer ID 284888BDBM284888(US10023576, Example 79 | N-(5-{4-amino-7-[1-(1,1-d...)
Affinity DataIC50: 4nMpH: 7.5 T: 2°CAssay Description:The ADP-Glo format PI3K assays were performed in Proxiplate 384-well plates (Perkin Elmer #6008280). The final assay volume was 2 μl prepared fr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent