BDBM285580 US10077269, Example 53::US10669279, Example 53::US9598421, Example 53::azetidin-1-yl[3-(4-fluoro-3,5-dimethylphenyl)imidazo[1,2-b]pyridazin-2-yl]methanone

SMILES: Cc1cc(cc(C)c1F)-c1c(nc2cccnn12)C(=O)N1CCC1

InChI Key: InChIKey=CTXZJNXACMKAGH-UHFFFAOYSA-N

Data: 12 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 285580   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Isoform 4 of cAMP-specific 3',5'-cyclic phosphodiesterase 4A (RD1) (Human)	BDBM285580 (US10077269, Example 53 | azetidin-1-yl[3-(4-fluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	17.8	n/a	n/a	n/a	n/a	n/a	n/a
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cAMP-specific 3',5'-cyclic phosphodiesterase 4B [122-736,S654A] (Human)	BDBM285580 (US10077269, Example 53 | azetidin-1-yl[3-(4-fluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	63.3	n/a	n/a	n/a	n/a	n/a	n/a
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Isoform 3 of cAMP-specific 3',5'-cyclic phosphodiesterase 4D (hPDE4D3) (Human)	BDBM285580 (US10077269, Example 53 | azetidin-1-yl[3-(4-fluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	153	n/a	n/a	n/a	n/a	n/a	n/a
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Isoform 3 of cAMP-specific 3',5'-cyclic phosphodiesterase 4D (hPDE4D3) (Human)	BDBM285580 (US10077269, Example 53 | azetidin-1-yl[3-(4-fluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.11E+3	n/a	n/a	n/a	n/a	n/a	n/a
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cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Human)	BDBM285580 (US10077269, Example 53 | azetidin-1-yl[3-(4-fluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	17.8	n/a	n/a	n/a	n/a	n/a	n/a
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cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Human)	BDBM285580 (US10077269, Example 53 | azetidin-1-yl[3-(4-fluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	63.3	n/a	n/a	n/a	n/a	n/a	n/a
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cAMP-specific 3',5'-cyclic phosphodiesterase 4C (Human)	BDBM285580 (US10077269, Example 53 | azetidin-1-yl[3-(4-fluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	153	n/a	n/a	n/a	n/a	n/a	n/a
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cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Human)	BDBM285580 (US10077269, Example 53 | azetidin-1-yl[3-(4-fluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.11E+3	n/a	n/a	n/a	n/a	n/a	n/a
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cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Human)	BDBM285580 (US10077269, Example 53 | azetidin-1-yl[3-(4-fluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	17.8	n/a	n/a	n/a	n/a	n/a	n/a
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cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Human)	BDBM285580 (US10077269, Example 53 | azetidin-1-yl[3-(4-fluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	63.3	n/a	n/a	n/a	n/a	n/a	n/a
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cAMP-specific 3',5'-cyclic phosphodiesterase 4C (Human)	BDBM285580 (US10077269, Example 53 | azetidin-1-yl[3-(4-fluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	153	n/a	n/a	n/a	n/a	n/a	n/a
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cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Human)	BDBM285580 (US10077269, Example 53 | azetidin-1-yl[3-(4-fluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.11E+3	n/a	n/a	n/a	n/a	n/a	n/a
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