BDBM285628 3-(4-cyano-5-fluoro-2-methyl-phenyl)-N-ethylimidazo[1,2-b]pyridazine-2-carboxamide::US10077269, Example 98::US10669279, Example 98::US9598421, Example 98

SMILES: CCNC(=O)c1nc2cccnn2c1-c1cc(F)c(cc1C)C#N

InChI Key: InChIKey=FKAXUOKPFFFYTF-UHFFFAOYSA-N

Data: 12 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 285628   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Isoform 4 of cAMP-specific 3',5'-cyclic phosphodiesterase 4A (RD1) (Human)	BDBM285628 (US10077269, Example 98 | 3-(4-cyano-5-fluoro-2-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	26.6	n/a	n/a	n/a	n/a	n/a	n/a
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cAMP-specific 3',5'-cyclic phosphodiesterase 4B [122-736,S654A] (Human)	BDBM285628 (US10077269, Example 98 | 3-(4-cyano-5-fluoro-2-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	62.7	n/a	n/a	n/a	n/a	n/a	n/a
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Isoform 3 of cAMP-specific 3',5'-cyclic phosphodiesterase 4D (hPDE4D3) (Human)	BDBM285628 (US10077269, Example 98 | 3-(4-cyano-5-fluoro-2-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	107	n/a	n/a	n/a	n/a	n/a	n/a
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Isoform 3 of cAMP-specific 3',5'-cyclic phosphodiesterase 4D (hPDE4D3) (Human)	BDBM285628 (US10077269, Example 98 | 3-(4-cyano-5-fluoro-2-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.32E+3	n/a	n/a	n/a	n/a	n/a	n/a
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cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Human)	BDBM285628 (US10077269, Example 98 | 3-(4-cyano-5-fluoro-2-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	26.6	n/a	n/a	n/a	n/a	n/a	n/a
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cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Human)	BDBM285628 (US10077269, Example 98 | 3-(4-cyano-5-fluoro-2-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	62.7	n/a	n/a	n/a	n/a	n/a	n/a
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cAMP-specific 3',5'-cyclic phosphodiesterase 4C (Human)	BDBM285628 (US10077269, Example 98 | 3-(4-cyano-5-fluoro-2-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	107	n/a	n/a	n/a	n/a	n/a	n/a
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cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Human)	BDBM285628 (US10077269, Example 98 | 3-(4-cyano-5-fluoro-2-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.32E+3	n/a	n/a	n/a	n/a	n/a	n/a
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cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Human)	BDBM285628 (US10077269, Example 98 | 3-(4-cyano-5-fluoro-2-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	26.6	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Human)	BDBM285628 (US10077269, Example 98 | 3-(4-cyano-5-fluoro-2-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	62.7	n/a	n/a	n/a	n/a	n/a	n/a
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cAMP-specific 3',5'-cyclic phosphodiesterase 4C (Human)	BDBM285628 (US10077269, Example 98 | 3-(4-cyano-5-fluoro-2-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	107	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Human)	BDBM285628 (US10077269, Example 98 | 3-(4-cyano-5-fluoro-2-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.32E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair