BDBM288685 (E)-3-(4-((6S,8R/6R,8S)-7-cyclopentyl-8-methyl-6,7,8,9-tetrahydro-3H-pyrazolo[4,3-f]isoquinolin-6-yl)-3,5-difluorophenyl)acrylic acid::US10087191, Example 103

SMILES: CC1Cc2c(ccc3[nH]ncc23)C(N1C1CCCC1)c1c(F)cc(\C=C\C(O)=O)cc1F

InChI Key: InChIKey=VOEBBSPDAIVMJW-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 288685   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G-protein coupled estrogen receptor 1 (Human)	BDBM288685 ((E)-3-(4-((6S,8R/6R,8S)-7-cyclopentyl-8-methyl-6,7...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.32	n/a	n/a	n/a	n/a	n/a	n/a
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