BDBM289878 2-Hydroxy-1-[(R)-3-(methyl-{6-[5-(2H-pyrazol-3-yl)-pyridin-2-yloxy]-naphthalen-2-ylmethyl}-amino)-pyrrolidin-1-yl]-ethanone (19)::US9573957, Example 19

SMILES: OCC(=O)N1CC[C@H](C1)NCc1ccc2cc(Oc3ccc(cn3)-c3ccn[nH]3)ccc2c1

InChI Key: InChIKey=HFRILWFYZRGBER-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 289878   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukotriene A-4 hydrolase (Human)	BDBM289878 (2-Hydroxy-1-[(R)-3-(methyl-{6-[5-(2H-pyrazol-3-yl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.630	n/a	n/a	n/a	n/a	7.5	25
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