BDBM289887 N-(1-{6-[5-(2H-Pyrazol-3-yl)-pyrimidin- 2-yloxy]-naphthalen-2-ylmethyl}- piperidin-4-yl)-acetamide::US9573957, Example 28

SMILES: CC(=O)NC1CCN(Cc2ccc3cc(Oc4ncc(cn4)-c4ccn[nH]4)ccc3c2)CC1

InChI Key: InChIKey=DEOSJDUAWLGEJV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 289887   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukotriene A-4 hydrolase (Human)	BDBM289887 (N-(1-{6-[5-(2H-Pyrazol-3-yl)-pyrimidin- 2-yloxy]-n...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.80	n/a	n/a	n/a	n/a	7.5	25
TBA									Citation and Details
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