BDBM289901 2-Methyl-1-(4-{6-[5-(2H-pyrazol-3- yl)-pyrimidin-2-yloxy]-naphthalen-2- ylmethyl}-piperazin-1-yl)-propan-1-one::US9573957, Example 41

SMILES: CC(C)C(=O)N1CCN(Cc2ccc3cc(Oc4ncc(cn4)-c4ccn[nH]4)ccc3c2)CC1

InChI Key: InChIKey=LSAGIKCWXLDSFY-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 289901   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukotriene A-4 hydrolase (Human)	BDBM289901 (2-Methyl-1-(4-{6-[5-(2H-pyrazol-3- yl)-pyrimidin-2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.970	n/a	n/a	n/a	n/a	7.5	25
TBA									Citation and Details
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