BDBM289986 1-(4-{6-[5-(2H-Pyrazol-3-yl)-pyridin-2-yloxy]-benzofuran-3-carbonyl}-piperazin-1-yl)-ethanone (112)::US9573957, Example 112

SMILES: CC(=O)N1CCN(CC1)C(=O)c1coc2cc(Oc3ccc(cn3)-c3ccn[nH]3)ccc12

InChI Key: InChIKey=SAUKQOWPDVGKJX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 289986   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukotriene A-4 hydrolase (Human)	BDBM289986 (1-(4-{6-[5-(2H-Pyrazol-3-yl)-pyridin-2-yloxy]-benz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.90	n/a	n/a	n/a	n/a	7.5	25
TBA									Citation and Details
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