BDBM291190 N-{4-[(3R,4R,5S)-3-Amino-4-hydroxy-5-methylpiperidin-1-yl]pyridin-3-yl}-7-(tetrahydro-2H-pyran-4-yl)quinoline-2-carboxamide::US9580418, Example 11::US9890162, Example 11

SMILES: C[C@H]1CN(C[C@@H](N)[C@@H]1O)c1ccncc1NC(=O)c1ccc2ccc(cc2n1)C1CCOCC1

InChI Key: InChIKey=ZCIAXCLJCAUHGJ-UHFFFAOYSA-N

Data: 6 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 291190   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Human)	BDBM291190 (US9580418, Example 11 | N-{4-[(3R,4R,5S)-3-Amino-4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<10	n/a	n/a	n/a	n/a	7.5	25
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					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Human)	BDBM291190 (US9580418, Example 11 | N-{4-[(3R,4R,5S)-3-Amino-4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	150	n/a	n/a	n/a	n/a	7.5	25
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					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Human)	BDBM291190 (US9580418, Example 11 | N-{4-[(3R,4R,5S)-3-Amino-4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<10	n/a	n/a	n/a	n/a	7.5	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Human)	BDBM291190 (US9580418, Example 11 | N-{4-[(3R,4R,5S)-3-Amino-4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Human)	BDBM291190 (US9580418, Example 11 | N-{4-[(3R,4R,5S)-3-Amino-4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Human)	BDBM291190 (US9580418, Example 11 | N-{4-[(3R,4R,5S)-3-Amino-4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair