BDBM292330 US10100057, Example 185::US11046702, Example 185::US9745310, Example 185

SMILES Cc1ccccc1-c1cnc2nc(COc3ccnc(F)c3)cn2n1

InChI Key InChIKey=PAKLUXZVRGNPJB-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 292330   

TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM292330(US10100057, Example 185 | US11046702, Example 185 ...)
Affinity DataEC50:  300nMT: 2°CAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM292330(US10100057, Example 185 | US11046702, Example 185 ...)
Affinity DataEC50:  300nMAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM292330(US10100057, Example 185 | US11046702, Example 185 ...)
Affinity DataEC50:  300nMAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent