BDBM295029 3-{6-Amino-5-[1-(2,2,2-trifluoro-ethyl)-1H-pyrazol-4-yl]-pyridin-3-yl}-4-methyl-N-(6-methyl-pyridin-2-yl)-benzenesulfonamide::US10112926, Example 1

SMILES: Cc1cccc(NS(=O)(=O)c2ccc(C)c(c2)-c2cnc(N)c(c2)-c2cnn(CC(F)(F)F)c2)n1

InChI Key: InChIKey=NSTFOXCDXMJUGH-UHFFFAOYSA-N

Data: 7 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 295029   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 3-kinase regulatory subunit alpha (Human)	BDBM295029 (3-{6-Amino-5-[1-(2,2,2-trifluoro-ethyl)-1H-pyrazol...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	190	n/a	n/a	n/a	n/a	7.5	25
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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Human)	BDBM295029 (3-{6-Amino-5-[1-(2,2,2-trifluoro-ethyl)-1H-pyrazol...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.05E+3	n/a	n/a	n/a	n/a	7.5	25
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Phosphatidylinositol 3-kinase catalytic subunit type 3 (Human)	BDBM295029 (3-{6-Amino-5-[1-(2,2,2-trifluoro-ethyl)-1H-pyrazol...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>9.10E+3	n/a	n/a	n/a	n/a	7.5	25
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Phosphatidylinositol 4-kinase beta (Human)	BDBM295029 (3-{6-Amino-5-[1-(2,2,2-trifluoro-ethyl)-1H-pyrazol...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.95E+3	n/a	n/a	n/a	n/a	7.5	25
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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Human)	BDBM295029 (3-{6-Amino-5-[1-(2,2,2-trifluoro-ethyl)-1H-pyrazol...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7	n/a	n/a	n/a	n/a	7.5	n/a
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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Human)	BDBM295029 (3-{6-Amino-5-[1-(2,2,2-trifluoro-ethyl)-1H-pyrazol...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	170	n/a	n/a	n/a	n/a	7.5	n/a
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Serine/threonine-protein kinase mTOR (Human)	BDBM295029 (3-{6-Amino-5-[1-(2,2,2-trifluoro-ethyl)-1H-pyrazol...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.37E+3	n/a	n/a	n/a	n/a	7.5	n/a
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