BDBM296860 2-(5-(1-(2-(Difluoromethoxy)phenyl)-1,2,3,4-tetrahydroimidazo[1,2-a:5,4-b′]dipyridin-8-yl)pyrimidin-2-yl)propan-2-ol::US10112944, Example 34

SMILES CC(C)(O)c1ncc(cn1)-c1ccc2nc3CCCN(c3n2c1)c1ccccc1OC(F)(F)F

InChI Key InChIKey=BXEVCQBRIJKBGK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 296860   

TargetTumor necrosis factor(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM296860(2-(5-(1-(2-(Difluoromethoxy)phenyl)-1,2,3,4-tetrah...)
Affinity DataIC50: 1.00E+3nMAssay Description:Test compounds serially diluted in DMSO were plated in an assay plate (Labcyte, Cat. #LP-0200) at final concentrations ranging from 0.004 μM to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
US Patent